Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23678359 | 0.88 | MAOB (0.38) | MAOBPDE2AMAOAKCNE1KCNQ1 | |
| SCHEMBL23678495 | 0.88 | MAOB (0.38) | MAOBPDE2AMAOAKCNE1KCNQ1 | |
| SCHEMBL23678388 | 0.88 | MAOB (0.38) | MAOBPDE2AMAOAKCNE1KCNQ1 | |
| SCHEMBL23678416 | 0.83 | MAOB (0.35) | MAOBPDE2AKCNE1KCNQ1KCNH2 | |
| SCHEMBL23678412 | 0.80 | KCNH2 (0.39) | MAOBKCNH2ALOX5CACNA1B | |
| SCHEMBL23678320 | 0.76 | MCL1 (0.37) | FFAR4 | |
| SCHEMBL23678409 | 0.75 | CYP17A1 (0.41) | PDE2ACYP2C9 | |
| SCHEMBL23678378 | 0.74 | PDE2A (0.37) | PDE2AKCNH2CYP2C9 | |
| SCHEMBL23678196 | 0.72 | MAOB (0.38) | MAOBPDE2AMAOAKCNH2CACNA1B | |
| SCHEMBL23678461 | 0.72 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854788-A1 | COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |