Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 16/20 | 0.72 |
| ▸ | JAK2 | O60674 | 13/20 | 0.72 |
| ▸ | JAK3 | P52333 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870786 | 0.93 | JAK1 (0.84) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL21870796 | 0.93 | JAK1 (0.84) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL30810073 | 0.93 | JAK1 (0.84) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL23678797 | 0.93 | JAK1 (0.73) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL30810106 | 0.93 | JAK1 (0.84) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL21870731 | 0.93 | JAK1 (0.84) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL21870682 | 0.92 | JAK1 (0.84) | JAK1JAK2 | |
| SCHEMBL21870693 | 0.90 | JAK1 (0.71) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL23678795 | 0.89 | JAK1 (0.83) | JAK1JAK2JAK3 | |
| SCHEMBL21870691 | 0.89 | JAK1 (0.77) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854793-A1 | AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |