Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21845297 | 0.86 | GAA (0.43) | GAAKMT2AALDH1A1NTRK1TSHR | |
| Hydrochloric Acid SCHEMBL21808300 | 0.85 | GAA (0.42) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL21808533 | 0.83 | HRH3 (0.48) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL23668147 | 0.83 | NTRK1 (0.46) | GAAKMT2AALDH1A1NTRK1TSHR | |
| Hydrochloric Acid SCHEMBL21808492 | 0.82 | HRH3 (0.47) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL23668124 | 0.81 | TSHR (0.52) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL23668130 | 0.81 | P2RY12 (0.43) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL21808515 | 0.81 | P2RY12 (0.43) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL23668142 | 0.81 | P2RY12 (0.43) | GAAKMT2AALDH1A1NTRK1TSHR | |
| SCHEMBL23668144 | 0.81 | P2RY12 (0.43) | GAAKMT2AALDH1A1NTRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854787-A1 | EDARAVONE PRODRUG COMPOUND AND PHARMACEUTICAL USE THEREOF IN TREATMENT OR ALLEVIATION OF NEURODEGENERATIVE OR MOTOR NEURON DISEASE | J2H Biotech Inc. (KR) | 2021-07-28 | — | — | EP | disclosed |