SCHEMBL236802

SCHEMBL236802

C#CC#CC[CH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769739 0.76
SCHEMBL16287908 0.73
SCHEMBL16288820 0.69
SCHEMBL16287996 0.67
SCHEMBL972049 0.66
SCHEMBL16288051 0.66
SCHEMBL3268270 0.65
SCHEMBL562805 0.64
SCHEMBL12678052 0.64
SCHEMBL5985939 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11964938-B2 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists CELON PHARMA S.A. (PL) 2024-04-23 US disclosed
EP-3737470-B9 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2024-03-13 EP disclosed
EP-3927703-B1 ANTIBACTERIALS BASED ON MONOCYCLIC FRAGMENTS COUPLED TO AMINOPIPERIDINE NAPHTHYRIDINE SCAFFOLD UNIV LJUBLJANI (SI) 2023-04-05 EP disclosed
EP-3737470-B1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2022-12-14 EP disclosed
US-20220023275-A1 Aqueous Based Pharmaceutical Formulations of 1,2-Dihydropyridine Compounds EISAI R&D MANAGEMENT CO., LTD. (JP) 2022-01-27 US disclosed
EP-3927703-A1 ANTIBACTERIALS BASED ON MONOCYCLIC FRAGMENTS COUPLED TO AMINOPIPERIDINE NAPHTHYRIDINE SCAFFOLD Univerza V Ljubljani (SI) 2021-12-29 EP disclosed
EP-3893844-A1 AQUEOUS BASED PHARMACEUTICAL FORMULATIONS OF 1,2-DIHYDROPYRIDINE COMPOUNDS Eisai R&D Management Co., Ltd. (JP) 2021-10-20 EP disclosed
CN-113226286-A Water-based pharmaceutical formulations of 1, 2-dihydropyridine compounds 卫材R&D管理有限公司 2021-08-06 CN disclosed
US-20200399198-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2020-12-24 US disclosed
EP-3737470-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2020-11-18 EP disclosed
US-20030078277-A1 Fused heterotricyclic compounds, process for preparing the compounds and drugs containing the same EISAI R&D MANAGEMENT CO., LTD. (JP) 2003-04-24 US disclosed
EP-1300396-A1 1,2-DIHYDROPYRIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF Eisai Co., Ltd. (JP) 2003-04-09 EP disclosed
EP-1292573-A2 SUBSTITUTED THIOACETAMIDES CEPHALON, INC. (US) 2003-03-19 EP disclosed
US-6492396-B2 Substituted thioacetamides CEPHALON, INC. 2002-12-10 US disclosed
US-20020183334-A1 Substituted thioacetamides CEPHALON, INC. 2002-12-05 US disclosed
EP-1254904-A1 NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-1254895-A1 NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-11-06 EP disclosed
EP-1238979-A1 FUSED HETEROTRICYCLIC COMPOUNDS, PROCESS FOR PREPARING THE COMPOUNDS AND DRUGS CONTAINING THE SAME Eisai Co., Ltd. (JP) 2002-09-11 EP disclosed
US-20020045629-A1 Substituted thioacetamides CEPHALON, INC. 2002-04-18 US disclosed
WO-2001087830-A2 SUBSTITUTED THIOACETAMIDES CEPHALON, INC. (US) 2001-11-22 WO disclosed