Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17729190 | 0.82 | IDO1 (0.50) | IDO1CYP3A4 | |
| SCHEMBL17729188 | 0.82 | IDO1 (0.50) | IDO1CYP3A4 | |
| SCHEMBL17747209 | 0.82 | IDO1 (0.43) | IDO1CYP3A4 | |
| SCHEMBL17747206 | 0.82 | IDO1 (0.43) | IDO1CYP3A4 | |
| SCHEMBL22808938 | 0.78 | IDO1 (0.50) | IDO1NR1I2CYP3A4CYP1A2CYP2C8 | |
| SCHEMBL23680246 | 0.76 | IDO1 (0.52) | IDO1CYP3A4 | |
| SCHEMBL17729200 | 0.75 | IDO1 (0.57) | IDO1CYP3A4 | |
| SCHEMBL17729203 | 0.75 | IDO1 (0.57) | IDO1CYP3A4 | |
| SCHEMBL17740943 | 0.75 | IDO1 (0.57) | IDO1CYP3A4 | |
| SCHEMBL18826787 | 0.72 | IDO1 (0.53) | IDO1CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854394-A1 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |