SCHEMBL23680441

SCHEMBL23680441

Cc1ccc(NC(=O)C(C(C)C)N2CCC(Oc3ccnc4ccc(F)cc34)CC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17740948 0.92 IDO1 (0.64) IDO1
SCHEMBL18806773 0.91 IDO1 (0.63) IDO1
SCHEMBL18806800 0.87 IDO1 (0.59) IDO1
SCHEMBL18806746 0.87 IDO1 (0.68) IDO1
SCHEMBL17729183 0.85 IDO1 (0.62) IDO1
SCHEMBL28544986 0.84 IDO1 (0.54) IDO1
SCHEMBL17729160 0.84 IDO1 (0.66) IDO1
SCHEMBL18806728 0.82 IDO1 (0.59) IDO1
SCHEMBL18806801 0.80 IDO1 (0.69) IDO1
SCHEMBL23707444 0.79 IDO1 (0.56) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3854394-A1 IMMUNOREGULATORY AGENTS Flexus Biosciences, Inc. (US) 2021-07-28 EP disclosed