Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.48 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680781 | 0.99 | HPGD (0.66) | HPGDADORA2AMGLLEGLN2MKNK1 | |
| SCHEMBL23680747 | 0.89 | HPGD (0.52) | HPGDADORA2AMGLLDDR1KDM1A | |
| SCHEMBL23680590 | 0.89 | HPGD (0.52) | HPGDADORA2AMGLLDDR1 | |
| SCHEMBL23680615 | 0.87 | HPGD (0.62) | HPGDADORA2AMGLL | |
| SCHEMBL23680822 | 0.87 | HPGD (0.74) | HPGDADORA2AMGLL | |
| SCHEMBL24942223 | 0.87 | HPGD (0.50) | HPGDMGLLEGLN2KDM1A | |
| SCHEMBL29257187 | 0.87 | HPGD (0.50) | HPGDMGLLEGLN2KDM1A | |
| SCHEMBL23680752 | 0.86 | HPGD (0.63) | HPGDADORA2AMGLL | |
| SCHEMBL23680748 | 0.86 | HPGD (0.66) | HPGDADORA2AMGLL | |
| SCHEMBL24463744 | 0.86 | HPGD (0.48) | HPGDMGLLEGLN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021151014-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |