Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | PLD2 | O14939 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680603 | 0.90 | HPGD (0.48) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23675236 | 0.89 | HPGD (0.47) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23675239 | 0.87 | HPGD (0.49) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23680607 | 0.87 | HPGD (0.51) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23675155 | 0.87 | HPGD (0.46) | HPGDMGLLLRRK2DDR1IRAK4 | |
| SCHEMBL23680775 | 0.83 | HPGD (0.47) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23680706 | 0.82 | HPGD (0.54) | HPGDMGLLLRRK2VNN1 | |
| SCHEMBL23680617 | 0.82 | HPGD (0.47) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23675201 | 0.82 | HPGD (0.54) | HPGDMGLLLRRK2DDR1VNN1 | |
| SCHEMBL23680616 | 0.82 | HPGD (0.61) | HPGDMGLLLRRK2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151014-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |