Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680706 | 0.88 | HPGD (0.54) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23680607 | 0.87 | HPGD (0.51) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23675234 | 0.86 | HPGD (0.50) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23675180 | 0.86 | HPGD (0.58) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23675236 | 0.85 | HPGD (0.47) | HPGDMGLLLRRK2VNN1DDR1 | |
| SCHEMBL23675201 | 0.85 | HPGD (0.54) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23680616 | 0.85 | HPGD (0.61) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL24463716 | 0.85 | HPGD (0.56) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23680713 | 0.84 | HPGD (0.53) | HPGDMGLLLRRK2VNN1ADRA1A | |
| SCHEMBL23680610 | 0.84 | HPGD (0.48) | HPGDMGLLLRRK2VNN1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151014-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |