Cetylpyridinium

Cetylpyridinium

SCHEMBL2369770

CCCCCCCCCCCCCCCC[n+]1ccccc1.CCCCCCCCCCCCCCCC[n+]1ccccc1.O=C([O-])C=Cc1ccccc1.O=C([O-])c1ccccc1O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Cetylpyridinium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.43
MAPT P10636 4/20 0.43
BCHE P06276 1/20 0.43
CYP2C19 P33261 1/20 0.43
EGFR P00533 2/20 0.43
KCNH2 Q12809 2/20 0.43
CHRM2 P08172 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
CHRM1 P11229 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
ABCB11 O95342 1/20 0.43
ESR1 P03372 1/20 0.43
PGR P06401 1/20 0.43
HTR1A P08908 1/20 0.43
DRD1 P21728 1/20 0.43
TBXA2R P21731 1/20 0.43
PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetylpyridinium SCHEMBL5455825 0.90 CHRM2 (0.53) MAPTEGFRKCNH2CHRM2ADRA2A
Cetylpyridinium SCHEMBL5455822 0.90 CHRM2 (0.53) MAPTEGFRKCNH2CHRM2ADRA2A
Cetylpyridinium SCHEMBL667616 0.89 CHRM2 (0.54) MAPTCYP2C19EGFRKCNH2CHRM2
Cetylpyridinium SCHEMBL666198 0.85 CHRM2 (0.50) MAPTEGFRKCNH2CHRM2ADRA2A
Cetylpyridinium SCHEMBL2369768 0.81 KMT2A (0.43) MAPTEGFRKCNH2CHRM2ADRA2A
Cetylpyridinium SCHEMBL28035036 0.79 CHRM2 (0.57) MAPTCYP2C19EGFRKCNH2CHRM2
Cinnamic Acid SCHEMBL8407375 0.79 MAPT (0.63) MAPTBCHECYP2C19KCNH2KMT2A
Cinnamic Acid SCHEMBL8407378 0.79 MAPT (0.63) MAPTBCHECYP2C19KCNH2KMT2A
Cetylpyridinium SCHEMBL666197 0.77 KDM4E (0.49) MAPTEGFRKCNH2CHRM2ADRA2A
Thiosalicylic Acid SCHEMBL31129192 0.76 CHRM2 (0.53) MAPTCYP2C19EGFRKCNH2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278134-B2 Dual functioning ionic liquids and salts thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-03-08 US disclosed
WO-2011110662-A1 SUPPORTED BIOLOGICALLY ACTIVE COMPOUNDS DANMARKS TEKNISKE UNIVERSITET (DK) 2011-09-15 WO disclosed