Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.80 |
| ▸ | CDK9 | P50750 | 11/20 | 0.80 |
| ▸ | CDK7 | P50613 | 7/20 | 0.70 |
| ▸ | CCNH | P51946 | 7/20 | 0.70 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073066 | 1.00 | CDK2 (0.80) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL29842260 | 0.93 | CDK2 (0.82) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23713224 | 0.93 | CDK2 (0.85) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19896533 | 0.93 | CDK2 (0.77) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19896534 | 0.93 | CDK2 (0.77) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19918818 | 0.91 | CDK2 (0.82) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL18051027 | 0.90 | CDK2 (0.77) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL18051036 | 0.90 | CDK2 (0.79) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19918819 | 0.89 | CDK7 (0.87) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL19918821 | 0.89 | CDK7 (0.87) | CDK2CDK9CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268000-B1 | PYRAZOLO[1,5-A][1,3,5]TRIAZINE AND PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES AS CDK INHIBITORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-08-04 | — | — | EP | disclosed |