SCHEMBL2369828

SCHEMBL2369828

CC(O)C(N)C(=O)N1CCCC1[C]=O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 19/20 0.60
DPP7 Q9UHL4 8/20 0.60
PREP P48147 3/20 0.60
DPP8 Q6V1X1 7/20 0.48
DPP9 Q86TI2 5/20 0.48
FAP Q12884 4/20 0.47
PITRM1 Q5JRX3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2369832 1.00 DPP4 (0.60) DPP4DPP7PREPDPP8DPP9
SCHEMBL2769140 0.89 DPP4 (0.75) DPP4DPP7PREPDPP8DPP9
SCHEMBL2769136 0.89 DPP4 (0.75) DPP4DPP7PREPDPP8DPP9
SCHEMBL17376044 0.89 DPP4 (0.52) DPP4DPP7PREPDPP8DPP9
SCHEMBL7312806 0.85 DPP4 (0.73) DPP4DPP7PREPDPP8DPP9
SCHEMBL7312802 0.85 DPP4 (0.73) DPP4DPP7PREPDPP8DPP9
SCHEMBL9840411 0.85 DPP4 (0.73) DPP4DPP7PREPDPP8DPP9
SCHEMBL2196155 0.84 DPP4 (0.78) DPP4DPP7DPP8DPP9FAP
SCHEMBL7021069 0.84 DPP4 (0.78) DPP4DPP7DPP8DPP9FAP
SCHEMBL7403443 0.84 DPP4 (0.78) DPP4DPP7DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9550806-B2 Immunogenic compositions against human progastrin peptides ONKOLOGIX LTD. (US) 2017-01-24 US disclosed
US-20140227301-A1 IMMUNOGENIC COMPOSITIONS AGAINST HUMAN PROGASTRIN PEPTIDES ONKOLOGIX LTD (US) 2014-08-14 US disclosed
US-8674064-B2 Immunogenic compositions against human progastrin peptides ONKOLOGIX LTD (US) 2014-03-18 US disclosed
CN-101797382-B Anti-human progastrin polypeptide immune composition QI SHENGMEI 2013-11-20 CN disclosed
US-20130064841-A1 IMMUNOGENIC COMPOSITIONS AGAINST HUMAN PROGASTRIN PEPTIDES ONKOLOGIX LTD 2013-03-14 US disclosed
WO-2011109106-A2 IMMUNOGENIC COMPOSITIONS AGAINST HUMAN PROGASTRIN PEPTIDES ONKOLOGIX LTD (US) 2011-09-09 WO disclosed
CN-101797382-A Anti-human progastrin polypeptide immune composition SHENGMEI QI 2010-08-11 CN disclosed
EP-0232165-B1 Diagnostic method for gonorrhea by assay of IgA1 fragments IMMUNOGON ASSOCIATES (US) 1994-04-27 EP disclosed
EP-0324130-A2 8-Glycine, 16-X, Des-19-Leucine-Calcitonin RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) 1989-07-19 EP disclosed
US-4795702-A Diagnostic method for gonorrhea by assay of IgA1 fragments IMMUNOGON ASSOCIATES (US) 1989-01-03 US disclosed
US-4469632-A REDUCTION OF SERUM CALCIUM CONCENTRATION ARMOUR PHARMACEUTICAL COMPANY (US) 1984-09-04 US disclosed
WO-1984003279-A1 DES-ASPARAGINE-3 CALCITONIN ARMOUR PHARMA (US) 1984-08-30 WO disclosed
WO-1984003280-A1 GLYCINE-8 CALCITONIN ARMOUR PHARMA (US) 1984-08-30 WO disclosed
US-4414149-A POLYPEPTIDE ARMOUR PHARMACEUTICAL COMPANY (US) 1983-11-08 US disclosed
US-4401593-A CYCLIC POLYPEPTIDES ARMOUR PHARMACEUTICAL COMPANY (US) 1983-08-30 US disclosed
US-4388235-A SYNTHETIC CALCITONIN ARMOUR PHARMACEUTICAL COMPANY (US) 1983-06-14 US disclosed