Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 3/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077992 | 1.00 | PDE4B (0.69) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL21783709 | 1.00 | PDE4B (0.69) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL21783705 | 1.00 | PDE4B (0.69) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL14498493 | 1.00 | PDE4B (0.69) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL7826036 | 0.89 | SLC6A2 (0.64) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL17847243 | 0.89 | PDE4B (0.56) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL3195681 | 0.89 | PDE4B (0.56) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL3195687 | 0.89 | PDE4B (0.56) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL22926179 | 0.89 | PDE4B (0.71) | PDE4BRORCTACR1SLC6A2SLC6A4 | |
| SCHEMBL20805969 | 0.89 | PDE4B (0.71) | PDE4BRORCTACR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |