Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 1.00 |
| ▸ | GRM3 | Q14832 | 10/20 | 1.00 |
| ▸ | GRM8 | O00222 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20730930 | 1.00 | GRM2 (1.00) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL20722216 | 1.00 | GRM2 (1.00) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL22130893 | 0.89 | GRM2 (0.80) | GRM2GRM3 | |
| SCHEMBL19508605 | 0.87 | GRM2 (0.78) | GRM2GRM3 | |
| SCHEMBL19508606 | 0.87 | GRM2 (0.78) | GRM2GRM3 | |
| SCHEMBL22130892 | 0.85 | GRM2 (0.74) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL20309304 | 0.84 | GRM2 (0.73) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL233370 | 0.84 | GRM2 (0.73) | GRM2GRM3GRM8GRM6 | |
| SCHEMBL7392651 | 0.83 | GRM2 (0.71) | GRM2GRM3GRM8 | |
| SCHEMBL8764439 | 0.81 | GRM2 (0.81) | GRM2GRM3GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445743-B1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2021-08-04 | — | — | EP | disclosed |