Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699623 | 0.85 | BTK (0.59) | BTK | |
| SCHEMBL23699612 | 0.83 | LIMK2 (0.53) | LIMK2 | |
| SCHEMBL2253308 | 0.81 | LIMK2 (0.49) | LIMK2 | |
| SCHEMBL16637073 | 0.80 | LRRK2 (0.57) | LIMK2 | |
| SCHEMBL15664955 | 0.78 | BTK (0.72) | BTK | |
| SCHEMBL2253934 | 0.76 | LRRK2 (0.48) | LIMK2 | |
| SCHEMBL2253944 | 0.76 | LRRK2 (0.48) | LIMK2 | |
| SCHEMBL29230309 | 0.75 | KIT (0.55) | BTK | |
| SCHEMBL15664432 | 0.74 | BTK (0.60) | BTK | |
| SCHEMBL3647730 | 0.72 | LIMK2 (0.74) | LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892534-B1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-08-04 | — | — | EP | claimed |
| EP-2892534-B1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-08-04 | — | — | EP | disclosed |