Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29245197 | 0.76 | — | — | |
| SCHEMBL10809981 | 0.76 | — | — | |
| SCHEMBL233908 | 0.76 | — | — | |
| Bicarbonate SCHEMBL570721 | 0.74 | CA1 (1.00) | CA1CA2CA9ALDH1A1TSHR | |
| Bicarbonate SCHEMBL6478072 | 0.74 | CA1 (1.00) | CA1CA2CA9ALDH1A1TSHR | |
| SCHEMBL440185 | 0.74 | — | — | |
| Bicarbonate SCHEMBL7794 | 0.74 | — | — | |
| Bicarbonate SCHEMBL1179 | 0.74 | — | — | |
| Bicarbonate SCHEMBL15271537 | 0.74 | — | — | |
| Bicarbonate SCHEMBL11066368 | 0.74 | CA1 (1.00) | CA1CA2CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11742523-B2 | Electrolyte solutions | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2023-08-29 | — | — | US | disclosed |
| EP-4097789-A1 | ELECTROLYTE SOLUTIONS | Ascend Performance Materials Operations LLC (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115023837-A | Electrolyte solution | 奥升德功能材料运营有限公司 | 2022-09-06 | — | — | CN | disclosed |
| WO-2021155250-A1 | ELECTROLYTE SOLUTIONS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2021-08-05 | — | — | WO | disclosed |
| US-20210242503-A1 | ELECTROLYTE SOLUTIONS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2021-08-05 | — | — | US | disclosed |