SCHEMBL23701092

SCHEMBL23701092

CCCC[SiH](I)CCCC

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.38
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701110 0.94
SCHEMBL25183187 0.90 TSHR (0.44) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL25204557 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL25173759 0.87 TSHR (0.50) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL23701086 0.87
SCHEMBL1040391 0.79
SCHEMBL23700994 0.77
SCHEMBL21382933 0.74
SCHEMBL8385732 0.69 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL153638 0.69 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
WO-2023100914-A1 METHOD FOR MANUFACTURING OLIGOFURAN SKELETON-CONTAINING POLYCARBOSILANE AND OLIGOFURAN SKELETON-CONTAINING POLYCARBOSILANE 国立大学法人群馬大学 2023-06-08 WO disclosed
WO-2023080042-A1 METHOD FOR PRODUCING OLIGOFURAN COMPOUND CONTAINING REACTIVE SILYL GROUP, AND OLIGOFURAN COMPOUND CONTAINING REACTIVE SILYL GROUP 国立大学法人群馬大学 2023-05-11 WO disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed