SCHEMBL2370129

SCHEMBL2370129

CCCCCCCCCCCCCC(C)(C)NCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
FAAH O00519 2/20 0.41
DNM1 Q05193 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TP53 P04637 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAOA P21397 1/20 0.40
PKM P14618 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
KCNH2 Q12809 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606363 1.00 EPHX2 (0.47) EPHX2L3MBTL1SIGMAR1FAAHDNM1
SCHEMBL2369686 1.00 EPHX2 (0.47) EPHX2L3MBTL1SIGMAR1FAAHDNM1
SCHEMBL5071108 1.00 EPHX2 (0.47) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Hydrochloric Acid SCHEMBL356747 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Hydrochloric Acid SCHEMBL3299241 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Hydrochloric Acid SCHEMBL2232233 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Bromide SCHEMBL6829956 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Bromide SCHEMBL2231411 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Hydrochloric Acid SCHEMBL11150761 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1
Hydrochloric Acid SCHEMBL8417309 0.98 EPHX2 (0.46) EPHX2L3MBTL1SIGMAR1FAAHDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853605-B1 INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS BRACCO IMAGING SPA (IT) 2014-09-10 EP claimed
EP-1232269-B1 METHOD FOR PURIFYING RECOMBINANT HEXOSE OXIDASE DANISCO (DK) 2009-02-04 EP claimed
EP-3031928-B1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO RAD INNOVATIONS (FR) 2019-11-20 EP disclosed
EP-3031928-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS Bio-Rad Innovations (FR) 2016-06-15 EP disclosed
EP-2542688-B1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO RAD INNOVATIONS (FR) 2016-05-11 EP disclosed
EP-2542688-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS Bio-Rad Innovations (FR) 2013-01-09 EP disclosed
WO-2011107703-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO-RAD PASTEUR (FR) 2011-09-09 WO disclosed
US-4129554-A PICRIC ACID, QUINONE, CHLORANIL, CYANOACETATE ESTER HITACHI CHEMICAL CO., LTD. (JP) 1978-12-12 US disclosed
US-4070416-A POLYFUNCTIONAL ISOCYANATES AND EPOXIDES, ISOCYANURATE-OXAZOLIDOLE POLYMERS HITACHI, LTD. (JA) 1978-01-24 US disclosed