Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.68 |
| ▸ | SRC | P12931 | 9/20 | 0.68 |
| ▸ | ABL1 | P00519 | 8/20 | 0.68 |
| ▸ | INSR | P06213 | 5/20 | 0.68 |
| ▸ | LCK | P06239 | 5/20 | 0.68 |
| ▸ | KIT | P10721 | 5/20 | 0.68 |
| ▸ | KDR | P35968 | 5/20 | 0.68 |
| ▸ | RET | P07949 | 5/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.68 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.68 |
| ▸ | LYN | P07948 | 4/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.68 |
| ▸ | FLT1 | P17948 | 4/20 | 0.68 |
| ▸ | FLT3 | P36888 | 4/20 | 0.68 |
| ▸ | JAK2 | O60674 | 3/20 | 0.68 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.68 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.68 |
| ▸ | CSF1R | P07333 | 3/20 | 0.68 |
| ▸ | MET | P08581 | 3/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050447 | 1.00 | IGF1R (0.68) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703163 | 1.00 | IGF1R (0.68) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL30051038 | 1.00 | IGF1R (0.68) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703119 | 1.00 | IGF1R (0.68) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703240 | 0.92 | IGF1R (0.57) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL30050475 | 0.92 | IGF1R (0.57) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703241 | 0.92 | IGF1R (0.57) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703153 | 0.90 | IGF1R (0.61) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL23703157 | 0.90 | IGF1R (0.61) | IGF1RSRCABL1INSRLCK | |
| SCHEMBL30049696 | 0.90 | IGF1R (0.61) | IGF1RSRCABL1INSRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-01-14 | — | — | US | disclosed |
| CN-115916966-A | STRAD binding agents and uses thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| EP-4097223-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195490-B2 | STRAD-binding agents and uses thereof | STRAP, STRA6, PLAUR | IGF1R 1979/4885SRC 1149/4885ABL1 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.