Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.62 |
| ▸ | BTK | Q06187 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098665 | 0.92 | CRBN (0.63) | CRBNBTKARALKITK | |
| SCHEMBL27176462 | 0.91 | CRBN (0.65) | CRBNBTKARITKDDB1 | |
| SCHEMBL27028395 | 0.89 | CRBN (0.63) | CRBNBTKARITKDDB1 | |
| SCHEMBL29132157 | 0.89 | CRBN (0.63) | CRBNBTKARITKDDB1 | |
| SCHEMBL29132165 | 0.89 | CRBN (0.62) | CRBNBTKARITKDDB1 | |
| SCHEMBL20046371 | 0.89 | CRBN (0.62) | CRBNBTKARALKITK | |
| SCHEMBL29058479 | 0.89 | CRBN (0.62) | CRBNBTKARALKITK | |
| SCHEMBL29579610 | 0.88 | CRBN (0.61) | CRBNBTKARALKITK | |
| SCHEMBL30182975 | 0.88 | CRBN (0.68) | CRBNBTKARALKDDB1 | |
| SCHEMBL26702869 | 0.88 | CRBN (0.71) | CRBNBTKARALKDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |