Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851731 | 0.85 | HTT (0.41) | KMT2AATM | |
| SCHEMBL17036522 | 0.85 | GRM5 (0.46) | DRD5P2RY6GRM5APPBACE1 | |
| SCHEMBL17036534 | 0.84 | GRM5 (0.43) | DRD5P2RY6GRM5APPBACE1 | |
| SCHEMBL31442843 | 0.83 | GRM5 (0.44) | GRM5HDAC1HDAC6FFAR1FFAR4 | |
| SCHEMBL7859984 | 0.81 | GRM5 (0.43) | GRM5APPHDAC1HDAC6FFAR1 | |
| SCHEMBL15957582 | 0.81 | DRD5 (0.36) | DRD5P2RY6GRM5APPBACE1 | |
| SCHEMBL8771565 | 0.78 | CYP1A1 (0.40) | GRM5HDAC1HDAC6FFAR1FFAR4 | |
| SCHEMBL10018714 | 0.76 | GRM5 (0.44) | GRM5HDAC1HDAC6FFAR1FFAR4 | |
| SCHEMBL7857769 | 0.76 | GRM5 (0.44) | GRM5HDAC1HDAC6FFAR1FFAR4 | |
| SCHEMBL3592439 | 0.74 | EPHX2 (0.41) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681870-B1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-08-04 | — | — | EP | disclosed |