Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785259 | 0.84 | DPP4 (0.57) | DPP4PNMTTAAR1BACE1NOS3 | |
| SCHEMBL27781520 | 0.78 | TNKS2 (0.53) | MAOBPLA2G7TNKS2CYP2A6BACE1 | |
| SCHEMBL15354395 | 0.78 | TNKS2 (0.53) | MAOBPLA2G7TNKS2CYP2A6BACE1 | |
| SCHEMBL3784027 | 0.77 | TAAR1 (0.48) | DPP4TNKS2TAAR1BACE1 | |
| SCHEMBL9294904 | 0.74 | DPP4 (0.57) | DPP4PNMTTAAR1NOS3NOS1 | |
| SCHEMBL2549337 | 0.73 | CYP2A6 (0.47) | MAOBPLA2G7TNKS2CYP2A6BACE1 | |
| SCHEMBL5963942 | 0.71 | TNKS2 (0.47) | MAOBPLA2G7TNKS2CYP2A6BACE1 | |
| SCHEMBL2548717 | 0.71 | AR (0.44) | MAOBPLA2G7TNKS2CYP2A6BACE1 | |
| SCHEMBL2688813 | 0.71 | MAOB (0.72) | DPP4MAOBPNMTTAAR1CYP2A6 | |
| SCHEMBL12653047 | 0.70 | CYP2A6 (0.47) | DPP4MAOBTNKS2CYP2A6BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |