Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370911 | 1.00 | PPARG (0.48) | PPARGPPARAALDH1A1F7F3 | |
| SCHEMBL6369893 | 0.85 | PPARG (0.58) | PPARGPPARAF7F3CYP19A1 | |
| SCHEMBL6369891 | 0.85 | PPARG (0.58) | PPARGPPARAF7F3CYP19A1 | |
| SCHEMBL21925330 | 0.85 | PPARG (0.58) | PPARGPPARAF7F3CYP19A1 | |
| SCHEMBL21925331 | 0.85 | PPARG (0.58) | PPARGPPARAF7F3CYP19A1 | |
| SCHEMBL7474661 | 0.77 | PPARG (0.35) | PPARGPPARAALDH1A1KMT2ALMNA | |
| SCHEMBL29033609 | 0.72 | F7 (0.65) | PPARGPPARAALDH1A1F7F3 | |
| SCHEMBL1655436 | 0.72 | F7 (0.65) | PPARGPPARAALDH1A1F7F3 | |
| SCHEMBL8067162 | 0.71 | F7 (0.50) | PPARGPPARAALDH1A1F7F3 | |
| SCHEMBL14166582 | 0.71 | FABP3 (0.66) | PPARGPPARAALDH1A1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547322-A2 | USE OF NITROCARBOXYLIC ACIDS FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF AGGRESSIVE HEALING PATTERNS | Dietz, Ulrich (DE) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113507-A2 | USE OF NITROCARBOXYLIC ACIDS FOR THE TREATMENT, DIAGNOSIS AND PROPHYLAXIS OF AGGRESSIVE HEALING PATTERNS | DIETZ ULRICH (DE) | 2011-09-22 | — | — | WO | disclosed |