Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449778 | 0.92 | CHRM2 (0.75) | CHRM2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL11094422 | 0.89 | CHRM2 (0.75) | CHRM2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4919923 | 0.89 | CHRM2 (0.75) | CHRM2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL4913672 | 0.87 | CHRM2 (0.79) | CHRM2MEN1KMT2ANPC1TDP1 | |
| SCHEMBL5032223 | 0.87 | CHRM2 (0.79) | CHRM2MEN1KMT2ANPC1TDP1 | |
| SCHEMBL4917450 | 0.87 | CHRM2 (0.79) | CHRM2MEN1KMT2ANPC1TDP1 | |
| SCHEMBL5378420 | 0.81 | SMN1; SMN2 (0.75) | CHRM2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9973111 | 0.81 | MEN1 (0.74) | CHRM2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL7899778 | 0.81 | CHRM2 (0.64) | CHRM2SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL14045032 | 0.81 | CHRM2 (0.64) | CHRM2MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3188722-B1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2021-08-04 | — | — | EP | disclosed |