Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370993 | 1.00 | CYP2C9 (0.47) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL12292862 | 1.00 | CYP2C9 (0.47) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL12294065 | 1.00 | CYP2C9 (0.47) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL5270672 | 0.96 | CYP2C9 (0.48) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL12292471 | 0.96 | CYP2C9 (0.48) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL15491433 | 0.91 | MEN1 (0.41) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL12294062 | 0.89 | MEN1 (0.41) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL12292861 | 0.89 | MEN1 (0.41) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL14261087 | 0.89 | MEN1 (0.41) | CYP2C9TSHRMEN1LMNAGAA | |
| SCHEMBL13609916 | 0.89 | MEN1 (0.41) | CYP2C9TSHRMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113719-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2011-09-22 | — | — | WO | disclosed |