Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 11/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732603 | 1.00 | HRH3 (0.40) | HRH3DRD4KEAP1SMN1; SMN2DRD3 | |
| SCHEMBL22732588 | 1.00 | HRH3 (0.40) | HRH3DRD4KEAP1SMN1; SMN2DRD3 | |
| SCHEMBL9936319 | 0.89 | HRH3 (0.43) | HRH3DRD4DRD3EPHX1DRD2 | |
| SCHEMBL10963996 | 0.86 | EPHX1 (0.46) | HRH3DRD4DRD3EPHX1DRD2 | |
| SCHEMBL9935981 | 0.85 | HRH3 (0.46) | HRH3DRD4DRD3EPHX1DRD2 | |
| SCHEMBL22463775 | 0.84 | EPHX1 (0.53) | HRH3DRD4DRD3EPHX1DRD2 | |
| SCHEMBL28285268 | 0.83 | EPHX1 (0.56) | HRH3DRD4DRD3EPHX1CYP1A2 | |
| SCHEMBL10682538 | 0.83 | EPHX1 (0.56) | HRH3DRD4DRD3EPHX1CYP1A2 | |
| SCHEMBL28224236 | 0.82 | DRD4 (0.35) | DRD4KEAP1SMN1; SMN2DRD3DRD2 | |
| SCHEMBL28223636 | 0.82 | DRD4 (0.35) | DRD4KEAP1SMN1; SMN2DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858832-A1 | TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |