Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | VDR | P11473 | 1/20 | 0.51 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26426698 | 0.93 | GPBAR1 (0.58) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL26426713 | 0.90 | CA1 (0.55) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL26424229 | 0.90 | GPBAR1 (0.51) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL23704699 | 0.90 | CA1 (0.55) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL23704697 | 0.90 | CA1 (0.55) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL26425460 | 0.84 | GPBAR1 (0.67) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL23704681 | 0.82 | GPBAR1 (0.60) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL23704682 | 0.82 | GPBAR1 (0.60) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL10518559 | 0.82 | CA1 (0.65) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A | |
| SCHEMBL433005 | 0.81 | GPBAR1 (0.83) | GPBAR1NR1H4TBXA2RSLC10A2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155167-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-05 | — | — | WO | disclosed |