Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.61 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710341 | 0.88 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23710349 | 0.88 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23704717 | 0.88 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23704718 | 0.88 | GPBAR1 (0.67) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL26424560 | 0.83 | GPBAR1 (0.62) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL26425472 | 0.83 | GPBAR1 (0.70) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23710505 | 0.83 | GPBAR1 (0.69) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23710337 | 0.80 | GPBAR1 (0.69) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23705048 | 0.80 | GPBAR1 (0.69) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL23705047 | 0.80 | GPBAR1 (0.69) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155167-A1 | BILE ACID-GCPII INHIBITOR CONJUGATES TO TREAT INFLAMMATORY DISEASES | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-05 | — | — | WO | disclosed |