SCHEMBL23712262

SCHEMBL23712262

CC1(C)c2ccccc2-c2ccc(-c3cccc(-c4ccc(-c5cc(-c6ccccn6)nc(-c6ccccn6)c5)cc4)c3)cc21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 17/20 0.47
CCR1 P32246 2/20 0.41
CCR5 P51681 2/20 0.41
CCR8 P51685 2/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
ALPL P05186 1/20 0.41
HSP90AA1 P07900 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23712268 1.00 PDK2 (0.47) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712263 0.99 PDK2 (0.48) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712269 0.96 PDK2 (0.46) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712265 0.96 PDK2 (0.50) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712250 0.95 PDK2 (0.51) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712264 0.94 PDK2 (0.46) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712114 0.91 PDK2 (0.48) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712270 0.91 PDK2 (0.48) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL23712267 0.91 PDK2 (0.48) PDK2CCR1CCR5CCR8KDM4E
SCHEMBL14508147 0.91 PDK2 (0.51) PDK2CCR1CCR5CCR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021152940-A1 COMPOUND, ORGANIC THIN-FILM LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE 東レ株式会社 2021-08-05 WO disclosed