SCHEMBL23713170

SCHEMBL23713170

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nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SELP P16109 2/20 0.65
▸ SELL P14151 1/20 0.65
▸ MAG P20916 7/20 0.61
▸ SIGLEC7 Q9Y286 6/20 0.57
▸ SELE P16581 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14648686 1.00 SELP (0.65) SELPSELLMAGSIGLEC7SELE
SCHEMBL16185999 0.96 SELP (0.64) SELPSELLMAGSIGLEC7SELE
SCHEMBL16188535 0.94 SELP (0.62) SELPSELLMAGSIGLEC7SELE
SCHEMBL29391699 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL29389517 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL29448496 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL29405702 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL13195877 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL29372449 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE
SCHEMBL13978771 0.91 SELP (0.73) SELPSELLMAGSIGLEC7SELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246221-A1 CHIMERIC ANTIGEN RECEPTOR TARGETING SIALYL LEWIS A AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2021-08-12 — — US disclosed
US-20210236554-A1 LOW DOSE RADIATION CONDITIONING FOR IMMUNOTHERAPY MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2021-08-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246221-A1 CHIMERIC ANTIGEN RECEPTOR TARGETING SIALYL LEWIS A AND USES THEREOF SIGLEC9, SIGLEC7, FCGR2A SELP 123/4885SELL 72/4885MAG 451/4885
US-20210236554-A1 LOW DOSE RADIATION CONDITIONING FOR IMMUNOTHERAPY TNFRSF9, HAVCR2, ICOS SELP 647/4885SELL 590/4885MAG 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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