Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714887 | 1.00 | KDM1A (0.44) | KDM1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL19280233 | 0.89 | KDM1A (0.47) | KDM1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL1810741 | 0.85 | KDM1A (0.50) | KDM1ADRD2DRD1DRD4DRD5 | |
| SCHEMBL14685848 | 0.79 | SLC6A2 (0.44) | HTR2AHTR2CHTR2BPRMT5WDR77 | |
| SCHEMBL10324533 | 0.79 | PRMT5 (0.38) | HTR2CPRMT5WDR77HDAC4HTR6 | |
| SCHEMBL17247328 | 0.79 | PRMT5 (0.41) | PRMT5WDR77CYP3A4MEN1KMT2A | |
| SCHEMBL14685875 | 0.79 | TAAR1 (0.44) | HTR2AHTR2CHTR2BPRMT5WDR77 | |
| SCHEMBL20117303 | 0.79 | HTR2C (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL20676202 | 0.79 | HTR2C (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL27054112 | 0.79 | TAAR1 (0.44) | HTR2AHTR2CHTR2BPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |