Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645051 | 0.83 | CA14 (0.39) | CA14CA12CA1CA7CA2 | |
| SCHEMBL6285387 | 0.82 | HDAC6 (0.33) | CA14CA12CA1CA7CA2 | |
| SCHEMBL20326295 | 0.80 | CA12 (0.39) | CA14CA12CA1CA7CA2 | |
| SCHEMBL2608081 | 0.79 | CA14 (0.49) | CA14CA12CA1CA7CA2 | |
| SCHEMBL567400 | 0.79 | CA14 (0.43) | CA14SSTR4HDAC1HDAC2 | |
| SCHEMBL567402 | 0.79 | CA14 (0.43) | CA14SSTR4HDAC1HDAC2 | |
| SCHEMBL27257668 | 0.79 | CA14 (0.37) | CA14CA12CA1CA7CA2 | |
| SCHEMBL20442569 | 0.78 | CA12 (0.42) | CA14CA12CA1CA7CA2 | |
| SCHEMBL567647 | 0.78 | CA14 (0.45) | CA14SSTR4HDAC1HDAC2 | |
| SCHEMBL567649 | 0.78 | CA14 (0.45) | CA14SSTR4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152149-A1 | RAS INHIBITORS AND METHODS OF USING THE SAME | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2021-08-05 | — | — | WO | disclosed |