Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716202 | 0.86 | CTBP2 (0.38) | CTBP2IDO1NPC1RAB9AL3MBTL1 | |
| SCHEMBL23715899 | 0.79 | IDO1 (0.37) | CTBP2SLC6A4IDO1NPC1RAB9A | |
| SCHEMBL23716099 | 0.79 | ANO1 (0.34) | LMNATAAR1 | |
| SCHEMBL23715894 | 0.77 | CYP2C9 (0.38) | SLC6A4IDO1NPC1RAB9AL3MBTL1 | |
| SCHEMBL23715915 | 0.70 | IDO1 (0.35) | SLC6A4IDO1NPC1RAB9AL3MBTL1 | |
| SCHEMBL27760048 | 0.69 | IDO1 (0.47) | CTBP2SLC6A4IDO1NPC1RAB9A | |
| SCHEMBL23716232 | 0.68 | IDO1 (0.36) | CTBP2SLC6A4IDO1NPC1RAB9A | |
| SCHEMBL12108029 | 0.67 | TAAR1 (0.43) | CTBP2SLC6A4IDO1NPC1RAB9A | |
| SCHEMBL23716034 | 0.67 | IDO1 (0.38) | CTBP2SLC6A4IDO1NPC1RAB9A | |
| SCHEMBL16234241 | 0.65 | IDO1 (0.48) | SLC6A4IDO1NPC1RAB9ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |