Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 20/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.68 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.64 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.64 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716172 | 0.85 | S1PR3 (0.71) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17664399 | 0.83 | S1PR3 (0.91) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL23715813 | 0.81 | S1PR3 (0.72) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17663988 | 0.81 | S1PR3 (0.74) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL19196428 | 0.81 | S1PR3 (0.72) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17663938 | 0.81 | S1PR3 (1.00) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17664432 | 0.80 | S1PR3 (0.73) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL19195650 | 0.79 | S1PR3 (0.72) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17664134 | 0.79 | S1PR3 (0.85) | S1PR3S1PR1S1PR4S1PR2S1PR5 | |
| SCHEMBL17663946 | 0.78 | S1PR3 (0.80) | S1PR3S1PR1S1PR4S1PR2S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |