Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791647 | 0.75 | TSHR (0.37) | TSHRALDH1A1PTPN1F7F3 | |
| SCHEMBL24501205 | 0.71 | PPARG (0.46) | TSHRPTPN1F7F3PPARG | |
| SCHEMBL2957252 | 0.70 | — | — | |
| SCHEMBL2957251 | 0.70 | — | — | |
| SCHEMBL1569416 | 0.70 | — | — | |
| SCHEMBL17529137 | 0.70 | — | — | |
| SCHEMBL1569414 | 0.70 | — | — | |
| 1,1-Dichloroethene SCHEMBL28166990 | 0.69 | TSHR (0.74) | TSHRALDH1A1MEN1CYP3A4KMT2A | |
| SCHEMBL6432081 | 0.68 | TSHR (0.82) | TSHRALDH1A1F7F3 | |
| SCHEMBL1602927 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |