Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480538 | 0.79 | TAAR1 (0.50) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL30444061 | 0.78 | TAAR1 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL248652 | 0.78 | TAAR1 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL6161546 | 0.78 | TAAR1 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL1338205 | 0.78 | TAAR1 (0.54) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL6740216 | 0.78 | TAAR1 (0.71) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL1143685 | 0.77 | IDO1 (0.50) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL2405448 | 0.76 | TAAR1 (0.47) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL1989705 | 0.76 | TAAR1 (0.52) | TAAR1KDM4EHTT | |
| SCHEMBL2372931 | 0.76 | TAAR1 (0.56) | TAAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547665-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113756-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-22 | — | — | WO | disclosed |
| CN-1119337-C | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1239957-A | Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| CN-1239955-A | Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides | BAYER AG (DE) | 1999-12-29 | — | — | CN | disclosed |
| CN-1044365-C | Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis | SANKYO CO (JP) | 1999-07-28 | — | — | CN | disclosed |