Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 3/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704631 | 1.00 | APP (0.37) | APPMAPTSNCALSSGBA1 | |
| SCHEMBL23720312 | 0.95 | APP (0.38) | APPMAPTSNCALSSGBA1 | |
| SCHEMBL23720318 | 0.94 | APP (0.37) | APPMAPTSNCALSSGBA1 | |
| SCHEMBL23720319 | 0.89 | APP (0.40) | APPMAPTSNCALSSGBA1 | |
| SCHEMBL23720317 | 0.86 | LSS (0.39) | APPMAPTSNCALSSGBA1 | |
| SCHEMBL23720528 | 0.84 | LSS (0.41) | APPMAPTSNCALSSKDM4E | |
| SCHEMBL23720314 | 0.84 | LSS (0.41) | APPMAPTSNCALSSKDM4E | |
| SCHEMBL23720315 | 0.84 | LSS (0.39) | APPMAPTSNCALSSKDM4E | |
| SCHEMBL23720524 | 0.84 | LSS (0.39) | APPMAPTSNCALSSKDM4E | |
| SCHEMBL23720493 | 0.84 | LSS (0.39) | APPMAPTSNCALSSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155006-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND USES THEREOF | LES LABORATOIRES SERVIER SAS (FR) | 2021-08-05 | — | — | WO | disclosed |