SCHEMBL23720442

SCHEMBL23720442

O=C(O)CNC(=O)NC(CCCCNC(=O)NCc1ccc(CC(=O)O)cc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 19/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17190075 0.91 FOLH1 (0.60) FOLH1
SCHEMBL15739460 0.88 FOLH1 (0.69) FOLH1
SCHEMBL23783595 0.84 FOLH1 (0.49) FOLH1
SCHEMBL22840080 0.81 FOLH1 (0.63) FOLH1
SCHEMBL18308654 0.81 FOLH1 (0.51) FOLH1
SCHEMBL22299972 0.80 ALB (0.54) FOLH1
SCHEMBL22840033 0.80 FOLH1 (0.76) FOLH1
SCHEMBL15739424 0.80 FOLH1 (0.58) FOLH1
SCHEMBL22300022 0.79 FOLH1 (0.63) FOLH1
SCHEMBL22839997 0.79 FOLH1 (0.77) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3875082-A1 CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS Endocyte, Inc. (US) 2021-09-08 — — EP disclosed
EP-3858341-A1 PSMA LIGAND-CONTAINING CONJUGATES FOR THE TREATMENT OF PROSTATE CANCER Endocyte, Inc. (US) 2021-08-04 — — EP disclosed
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