Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120474 | 1.00 | APP (0.40) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL14211685 | 1.00 | APP (0.40) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720528 | 0.95 | LSS (0.41) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720518 | 0.95 | LSS (0.41) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720314 | 0.95 | LSS (0.41) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720320 | 0.90 | APP (0.38) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL1284075 | 0.89 | KDM4E (0.42) | APPMAPTKDM4ELSSKMT2A | |
| SCHEMBL23720524 | 0.89 | LSS (0.39) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720493 | 0.89 | LSS (0.39) | APPMAPTSNCAKDM4ELSS | |
| SCHEMBL23720315 | 0.89 | LSS (0.39) | APPMAPTSNCAKDM4ELSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155006-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND USES THEREOF | LES LABORATOIRES SERVIER SAS (FR) | 2021-08-05 | — | — | WO | disclosed |