Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 18/20 | 0.55 |
| ▸ | HTR2A | P28223 | 12/20 | 0.55 |
| ▸ | HTR1A | P08908 | 10/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055020 | 0.94 | DRD3 (0.63) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL23721086 | 0.92 | DRD3 (0.60) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL12930991 | 0.92 | DRD3 (0.60) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL22267820 | 0.91 | DRD3 (0.59) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL12930979 | 0.90 | DRD3 (0.66) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL18388442 | 0.90 | DRD3 (0.58) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL12930981 | 0.89 | DRD3 (0.65) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL1057074 | 0.89 | DRD3 (0.56) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL12931011 | 0.88 | DRD3 (0.64) | DRD3DRD2HTR2AHTR1ADRD1 | |
| SCHEMBL12930989 | 0.88 | DRD3 (0.64) | DRD3DRD2HTR2AHTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445343-B1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | ALKERMES PHARMA IRELAND LTD (IE) | 2021-08-04 | — | — | EP | disclosed |