Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601312 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682595 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682625 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682626 | 1.00 | PDE5A (0.66) | PDE5A | |
| Citric Acid SCHEMBL21682532 | 0.95 | PDE5A (0.59) | PDE5A | |
| Citric Acid SCHEMBL23924112 | 0.95 | PDE5A (0.59) | PDE5A | |
| Citric Acid SCHEMBL30052405 | 0.95 | PDE5A (0.59) | PDE5A | |
| SCHEMBL23750727 | 0.94 | PDE5A (0.64) | PDE5A | |
| SCHEMBL24402190 | 0.94 | PDE5A (0.67) | PDE5A | |
| SCHEMBL21682583 | 0.93 | PDE5A (0.66) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100014-A1 | COMPOSITIONS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | Nicox S.A. (FR) | 2022-12-14 | — | — | EP | claimed |
| WO-2021156275-A1 | COMPOSITIONS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | NICOX S.A. (FR) | 2021-08-12 | — | — | WO | claimed |
| EP-4100014-A1 | COMPOSITIONS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | Nicox S.A. (FR) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021156275-A1 | COMPOSITIONS FOR THE TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION | NICOX S.A. (FR) | 2021-08-12 | — | — | WO | disclosed |