Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.48 |
| ▸ | PDCD1LG2 | Q9BQ51 | 18/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30432853 | 1.00 | CD274 (0.48) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL25167985 | 0.92 | CD274 (0.51) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30433249 | 0.89 | PDCD1LG2 (0.60) | CD274PDCD1LG2 | |
| SCHEMBL23726122 | 0.89 | PDCD1LG2 (0.60) | CD274PDCD1LG2 | |
| SCHEMBL30433225 | 0.87 | PDCD1LG2 (0.52) | CD274PDCD1LG2 | |
| SCHEMBL30432694 | 0.87 | PDCD1LG2 (0.52) | CD274PDCD1LG2 | |
| SCHEMBL23726882 | 0.87 | PDCD1LG2 (0.52) | CD274PDCD1LG2 | |
| SCHEMBL23726118 | 0.83 | CD274 (0.56) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL29983330 | 0.82 | CD274 (0.54) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30433113 | 0.82 | PDCD1LG2 (0.56) | CD274PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100381-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021158481-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2021-08-12 | — | — | WO | disclosed |