Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373885 | 0.96 | DHODH (0.59) | DHODHTSHRPDE10ACTSAPTGFR | |
| SCHEMBL2372979 | 0.91 | DHODH (0.49) | DHODHCTSAPTGFR | |
| SCHEMBL2373164 | 0.90 | DHODH (0.56) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373118 | 0.89 | DHODH (0.60) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2372773 | 0.88 | DHODH (0.59) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373877 | 0.87 | DHODH (0.49) | DHODHCTSAPTGFR | |
| SCHEMBL2373648 | 0.87 | DHODH (0.60) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373114 | 0.87 | DHODH (0.62) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2373336 | 0.85 | DHODH (0.62) | DHODHTSHRPDE10APTGFR | |
| SCHEMBL2463806 | 0.84 | DHODH (0.54) | DHODHTSHRPDE10ACTSAPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |