Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683276 | 0.88 | LRRK2 (0.41) | LRRK2PTK2 | |
| SCHEMBL17683275 | 0.80 | EGFR (0.41) | LRRK2 | |
| SCHEMBL19254675 | 0.79 | EGFR (0.44) | LRRK2 | |
| SCHEMBL19254885 | 0.78 | LRRK2 (0.42) | LRRK2PTK2 | |
| SCHEMBL19532546 | 0.78 | LRRK2 (0.36) | LRRK2 | |
| SCHEMBL17683167 | 0.77 | EGFR (0.58) | — | |
| SCHEMBL19254673 | 0.74 | GRM2 (0.36) | LRRK2PTK2 | |
| SCHEMBL17683380 | 0.72 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL17682938 | 0.72 | EGFR (0.41) | LRRK2 | |
| SCHEMBL23729091 | 0.72 | EGFR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-B1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) | 2021-08-04 | — | — | EP | disclosed |