⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083926 | 0.76 | — | — | |
| SCHEMBL14338174 | 0.72 | — | — | |
| SCHEMBL17439191 | 0.72 | — | — | |
| SCHEMBL24408876 | 0.72 | — | — | |
| SCHEMBL24148064 | 0.69 | — | — | |
| SCHEMBL9563151 | 0.67 | — | — | |
| SCHEMBL1555786 | 0.65 | — | — | |
| SCHEMBL1555792 | 0.65 | — | — | |
| SCHEMBL1220456 | 0.65 | — | — | |
| SCHEMBL1220458 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-B1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) | 2021-08-04 | — | — | EP | disclosed |