Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852566 | 0.82 | TAAR1 (0.50) | TAAR1AOC3TRPA1RIPK1HTR2A | |
| SCHEMBL5852562 | 0.82 | TAAR1 (0.50) | TAAR1AOC3TRPA1RIPK1HTR2A | |
| SCHEMBL3715025 | 0.80 | HTR2A (0.46) | TAAR1TRPA1HTR2AHRH1LMNA | |
| SCHEMBL1256 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL4314053 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL25392233 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL2838538 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL19285046 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E | |
| SCHEMBL14191123 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1 | |
| SCHEMBL3022203 | 0.79 | TAAR1 (0.52) | TAAR1AOC3TRPA1RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210277200-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. | 2021-09-09 | — | — | US | claimed |
| US-11015034-B2 | Malonates and derivatives for in-situ films | ZEPHYROS, INC. (US) | 2021-05-25 | — | — | US | claimed |
| US-20190169396-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. | 2019-06-06 | — | — | US | claimed |
| CN-109476955-A | Malonic esters and derivatives for in situ membranes | 泽费罗斯股份有限公司 | 2019-03-15 | — | — | CN | claimed |
| WO-2017184986-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. (US) | 2017-10-26 | — | — | WO | claimed |
| US-20210277200-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. | 2021-09-09 | — | — | US | disclosed |
| US-11015034-B2 | Malonates and derivatives for in-situ films | ZEPHYROS, INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20190169396-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. | 2019-06-06 | — | — | US | disclosed |
| CN-109476955-A | Malonic esters and derivatives for in situ membranes | 泽费罗斯股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| WO-2017184986-A1 | MALONATES AND DERIVATIVES FOR IN-SITU FILMS | ZEPHYROS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |
| EP-2547665-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113756-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-22 | — | — | WO | disclosed |
| EP-1235808-A2 | TRICYCLIC ANALGESICS | WARNER-LAMBERT COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2000075116-A2 | TRICYCLIC ANALGESICS | WARNER-LAMBERT COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
| EP-0414200-B1 | Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof | OTSUKA PHARMA CO LTD (JP) | 1995-08-02 | — | — | EP | disclosed |
| CN-1028528-C | Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl) pyrazolo [1,5-a]-1,3,5-triazines | OTSUKA PHARMA CO LTD (JP) | 1995-05-24 | — | — | CN | disclosed |
| US-5137887-A | Xanthine oxidase inhibitors, antipodagric agents | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1992-08-11 | — | — | US | disclosed |
| CN-1049664-A | Optically active 4-hydroxyl-8-(3-low-alkoxy-4-phenyl sulfinyl phenyl) pyrazolo [1,5-α]-1,3,5-triazines salt and method for making thereof | OTSUKA PHARMA CO LTD (JP) | 1991-03-06 | — | — | CN | disclosed |
| EP-0414200-A2 | Salts of optically active 4-hydroxy-8-(3-lower alkoxy-4-phenylsulfinylphenyl)pyrazolo [1,5-a]-1,3,5-triazines and a process for production thereof | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |