Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826087 | 0.89 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2DNM1CA2 | |
| SCHEMBL1825228 | 0.89 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2DNM1CA2 | |
| SCHEMBL26707240 | 0.84 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2CA2CA12 | |
| SCHEMBL24146356 | 0.84 | EPHX2 (0.42) | MEN1KMT2ASMN1; SMN2DNM1EPHX2 | |
| SCHEMBL23518688 | 0.82 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2CA2CA12 | |
| SCHEMBL22302279 | 0.82 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL24764287 | 0.81 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2CA2CA12 | |
| SCHEMBL8956512 | 0.81 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2DNM1CA2 | |
| SCHEMBL22856326 | 0.80 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2EPHX2MCL1 | |
| SCHEMBL22124651 | 0.79 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2DNM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |