Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 19/20 | 0.57 |
| ▸ | INSR | P06213 | 4/20 | 0.57 |
| ▸ | LCK | P06239 | 3/20 | 0.57 |
| ▸ | KIT | P10721 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | RET | P07949 | 2/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.57 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | BTK | Q06187 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 2/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982281 | 1.00 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL31327279 | 1.00 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL31327291 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL23732495 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL28982321 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL31327283 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL28982338 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL23732490 | 0.91 | IGF1R (0.57) | IGF1RINSRLCKKITKDR | |
| SCHEMBL23732413 | 0.88 | IGF1R (0.69) | IGF1RINSRLCKKITKDR | |
| SCHEMBL31327275 | 0.88 | IGF1R (0.69) | IGF1RINSRLCKKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916966-A | STRAD binding agents and uses thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |