Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465335 | 0.90 | KDM4E (0.57) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL2351133 | 0.86 | KDM4E (0.57) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| Acetic Acid SCHEMBL28784357 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| Acetic Acid SCHEMBL8540615 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| Acetic Acid SCHEMBL6056055 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA | |
| Acetic Acid SCHEMBL28154484 | 0.84 | HIF1A (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| Hydrochloric Acid SCHEMBL3889042 | 0.84 | KDM4E (0.55) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL2211080 | 0.82 | SLC6A2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| SCHEMBL9539267 | 0.82 | KDM4E (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1KDM4E | |
| Phentermine SCHEMBL8142147 | 0.80 | SLC6A2 (0.79) | SMN1; SMN2HIF1ASLC6A2TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2899592-A1 | Coated substrate comprising a dual wavelength image-forming particulate composition and a process for making said composition | INTERNATIONAL PAPER COMPANY (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20150185608-A1 | IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT | INTERNATIONAL PAPER COMPANY | 2015-07-02 | — | — | US | disclosed |
| US-8980523-B2 | Imaging particulates, paper and process, and imaging of paper using dual wavelength light | INTERNATIONAL PAPER COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| EP-2340463-B1 | IMAGING PARTICULATE COMPOSITION AND IMAGING PROCESS USING DUAL WAVELENGTH LIGHT | INT PAPER CO (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140080044-A1 | Imaging Particulates, Paper and Process, and Imaging of Paper Using Dual Wavelength Light | INTERNATIONAL PAPER COMAPNY (US) | 2014-03-20 | — | — | US | disclosed |
| US-8586279-B2 | Imaging particulates, paper and process, and imaging of paper using dual wavelength light | INTERNATIONAL PAPER COMPANY (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120003592-A1 | IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT | INTERNATIONAL PAPER COMAPNY (US) | 2012-01-05 | — | — | US | disclosed |
| US-8053160-B2 | Imaging compositions and methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2011-11-08 | — | — | US | disclosed |
| US-8048606-B2 | Imaging methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2011-11-01 | — | — | US | disclosed |
| US-7977026-B2 | Imaging methods | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2011-07-12 | — | — | US | disclosed |
| EP-0215453-B1 | PHOTOIMAGING COMPOSITION CONTAINING ADMIXTURE OF LEUCO DYE AND 2,4,5-TRIPHENYLIMIDAZOLYL DIMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-13 | — | — | EP | disclosed |
| EP-0215453-A2 | Photoimaging composition containing admixture of leuco dye and 2,4,5-triphenylimidazolyl dimer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4622286-A | Photoimaging composition containing admixture of leuco dye and 2,4,5-triphenylimidazolyl dimer | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0024629-B1 | PHOTOIMAGING COMPOSITION COMPRISING A 2,4,5-TRIPHENYLIMIDAZOLYL DIMER AND AT LEAST ONE COMPOUND SELECTED FROM THE GROUP CONSISTING OF A LEUCO DYE AND A POLYMERIZABLE ETHYLENICALLY UNSATURATED MONOMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-04 | — | — | EP | disclosed |
| EP-0046271-B1 | PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0046271-A1 | Photosensitive compositions and elements containing substituted hydroxylamine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4311783-A | Dimers derived from unsymmetrical 2,4,5,-triphenylimidazole compounds as photoinitiators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4298678-A | PHOTOOXIDANT AND LEUCO DYE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0024629-A2 | Photoimaging composition comprising a 2,4,5-triphenylimidazolyl dimer and at least one compound selected from the group consisting of a leuco dye and a polymerizable ethylenically unsaturated monomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-11 | — | — | EP | disclosed |
| US-4252887-A | HIGH SPEED IMAGING; PHOTOSENSITIVE TO LONGER WAVELENGTHS; USED WITH PHOTOPOLYMERIZABLE OLEFIN; OVERLAY FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |