SCHEMBL23734759

SCHEMBL23734759

CC1CC(C)(C)CC(c2ccc(O)cc2)(c2ccc(OC(=O)OI)cc2)C1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.67
ESR2 Q92731 1/20 0.67
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
XBP1 P17861 1/20 0.37
ELANE P08246 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22003015 0.93 ESR1 (0.74) ESR1ESR2GAAMAPTXBP1
SCHEMBL22003013 0.88 ESR1 (0.67) ESR1ESR2GAAMAPTXBP1
SCHEMBL22003017 0.88 ESR1 (0.67) ESR1ESR2GAAMAPTXBP1
SCHEMBL19823257 0.86 ESR1 (0.72) ESR1ESR2GAAMAPTXBP1
SCHEMBL3892405 0.86 ESR1 (0.72) ESR1ESR2GAAMAPTXBP1
Bicarbonate SCHEMBL5398499 0.85 ESR1 (0.70) ESR1ESR2GAAMAPTXBP1
SCHEMBL16394592 0.84 ESR1 (0.58) ESR1ESR2GAAMAPTALDH1A1
SCHEMBL22003016 0.83 ESR1 (0.57) ESR1ESR2GAAMAPTALDH1A1
SCHEMBL16395145 0.83 ESR1 (0.57) ESR1ESR2GAAMAPTALDH1A1
SCHEMBL21583279 0.82 ESR1 (0.60) ESR1ESR2GAAMAPTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3580258-B1 OLIGOMERIC POLYOL COMPOSITIONS PRESIDIUM USA INC (US) 2021-08-11 EP disclosed